These are my numbers...
Yes a 22 X 22 is a big wheel for 1 ½ shafting. HP does not break shafts reduction gears & wheel sizes do that. A 20” wheel has a min bore of 1 ¼ up to a max bore of 1 ¾
A 22” wheel has a min bore of 1 3/8 to a max of 2” so 1 ¾ puts you in the sweet spot with that size wheel. Plus with a single screw boat the last thing you need is a snapped shaft.
As for your boat, lets see how efficient she is:
Right now i am cruising at about 2150 @15knts and 2600 for about 19.5 knts.
With a 22 X 18 Wheel
At 2600 RPMs you are getting 77 % wheel efficiency 100% efficiency would put you at 25.69 knots, which you never get with a keeled boat. 85% is about the most, therefore you are doing pretty wheel at 2600 RPMs with your current wheel.
However at 2150 RPMs you really drop off to only 71% efficiency.
Based on the 71 % @ 2150 RPMs you would get better performance & speed with more RPMs at Cruising speed. I would try running the boat @ 2300 to 2400 RPMs. Your miles per gallon should also increase.
Based on all of this lets figure your boat out with a 2:0 gear a 22 X 22 wheel and 84% efficiency:
At 2600 RPMs with a 22 X 22 wheel at 84% you would top out at 19.78 Knots
At 2150 RPMs with the 22 X 22 wheel at 84% you would cruise at 16,36 Knots
Those are my numbers the reduction gear change you would pick up 1.36 knots @ cruising speed & .25 knots WOT.
I would say you are where you want to be unless you want to spend about $7,000 plus for a gear, wheel, shaft & bearings.